Associate Scientist, Discovery Chemistry

Company: Disability Solutions
Location: Spring House
Posted on: February 15, 2025

Job Description:

Johnson & Johnson is hiring for an Associate Scientist, Discovery Chemistry to join our team in Spring House, PA.At Johnson & Johnson, we believe health is everything. Our strength in healthcare innovation empowers us to build a world where complex diseases are prevented, treated, and cured, where treatments are smarter and less invasive, and solutions are personal. Through our expertise in Innovative Medicine and MedTech, we are uniquely positioned to innovate across the full spectrum of healthcare solutions today to deliver the breakthroughs of tomorrow, and profoundly impact health for humanity. Learn more at https://www.jnj.com/.For more than 130 years, diversity, equity & inclusion (DEI) has been a part of our cultural fabric at Johnson & Johnson and woven into how we do business every day. Rooted in Our Credo, the values of DEI fuel our pursuit to create a healthier, more equitable world. Our diverse workforce and culture of belonging accelerate innovation to solve the world's most pressing healthcare challenges.We know that the success of our business - and our ability to deliver meaningful solutions - depends on how well we understand and meet the diverse needs of the communities we serve. Which is why we foster a culture of inclusion and belonging where all perspectives, abilities and experiences are valued and our people can reach their potential.At Johnson & Johnson, we all belong.We are seeking an experienced, highly skilled, and motivated analytical and separation scientist to join our team in Spring House, PA as an Associate Scientist in Discovery Chemistry. In this laboratory-based position, the successful candidate will provide high throughput purification to support medicinal chemistry efforts, with a particular emphasis on peptide projects. This includes purifying compounds from focused chemical libraries or singleton samples at --g to grams using various techniques, such as mass-directed reversed-phase high performance liquid chromatography (RP-HPLC). The candidate will work closely with scientists from Discovery Chemistry and Discovery Process Research to expedite compound design-synthesis-test iterations. Strong communication skills and the ability to thrive in a team-oriented, results-driven environment are essential. Additionally, the candidate must possess strong interpersonal skills to influence collaboration in a multidisciplinary setting.Key Responsibilities:

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• Develop, implement, operate, optimize, and maintain efficient workflows and instrumentations in a highly automated setting for the analysis and purification of compounds from medicinal chemistry projects, particularly in peptide synthesis singletons and libraries utilizing RP-HPLC.
• Conduct high-throughput purification work, including crude sample method screening, purification, quality control, and distribution of purified samples specifically for peptide applications using reversed-phase HPLC.
• Optimize workflows for maximum efficiency and deliver fast-turnaround purification services tailored to peptide needs.
• Develop methods to address various requirements in peptide drug discovery and related modalities.
• Present data and reports at internal and external scientific meetings as appropriate, focusing on advancements in peptide purification strategies.
• Act as the senior member in the laboratory by providing hand-on training of new hires, mentoring junior team members, and leading lab operations efforts.
• Collaborate with the vendors to implement new instrumentation, troubleshoot issues and ensure the smooth operation of instruments.\r\r

Keywords: Disability Solutions, Philadelphia , Associate Scientist, Discovery Chemistry, Other , Spring House, Pennsylvania